2016年8月28日星期日

PNAS: used to estimate the molecular clock ancient genome era

Shakespeare Glen University and Harvard Medical refrigerator School researchers report genetics method for estimating the age of the ancient human remains. An accurate estimate of ancient human specimen's ancient dna analysis is the key to the interpretation. Although radiocarbon dating of this specimen's estimated standard tool is very accurate, it may be because of pollution and bias. Priya Moorjani and colleagues developed a complementary method for determination of the ancient genome era, since the method is compared between Neanderthal gene infiltrated into ancient and modern non-Africans from the common ancestor of ancient and modern non-Africans the cumulative number of genetic recombination. Most non-Africans have from 2% Neanderthal lineage composition humans and Neanderthals about 50,000 years ago happened due to hybridization.

Assuming that each generation recombination rate is substantially constant, since the Neanderthal DNA was first introduced, the number of recombination can be used as a molecular clock, thereby infer between an ancient genome and the genomes of contemporary Lost intergenerational number. The authors use genome sequencing data, five ancient human specimens from North America, Europe and Siberia tested their method, radiocarbon dating data from 1.2 million years ago to 4.5 million years ago, the age estimate obtained with the radiocarbon consistent year.

Annual counting using radiocarbon dating and to intergenerational count Neanderthal introgression correlation years, the authors estimate the intergenerational history each generation interval is about 28 years. According to the authors, this estimate compliance with the contemporary western Eurasians.

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